< Ausstellung bei der "Langen Nacht der Wissenschaft" in Jena
05.12.2011 13:34 Age: 7 yrs

Exhibition at "Lange Nacht der Wissenschaft" in Jena

Biotech Cellulose: An innovative bio- and implant material with exciting properties and functions

For the cultivation of living cells, for closure of defects of internal organs and for replacement of organs such as blood vessels bio- and implant materials are needed. These materials may come from the people themselves or from animals, or they may be artificial products such as titanium, ceramic or Teflon. What is missing are materials that are of natural origin - but do not come from human or animal - and are as similar as possible in relation to the tissues of the body. They should be very good biocompatible and incorporated into the body.

Against this background, in Polymet Jena and Jenpolymers Ltd. systematic research and development work is carried out on novel cellulosic materials. Cellulose is the main structure polymer of the plant world and a familiar material for the people using it daily in the form of paper, building materials, cosmetics and sanitary products, as well as clothing. For the development of bio-and implant materials a special type of cellulose is used, the especially pure and body-friendly Biotech cellulose.

Biotech cellulose (BC) is a dimensionally stable cellulose hydrogel biotechnologically produced in a simple manner from glucose (dextrose) using acetic acid bacteria in an aqueous culture medium. The BC hydrogels can be created as fleeces, films, shaped bodies, hollow bodies, and dispersions of almost any dimension. They consist of a hierarchical 3D cellulose nanofiber network with a controllable water content up to 99% and are transparent for liquids, ions and small molecules as well as for light. With this profile BC differs fundamentally from the traditional wood cellulose, as found in paper and pulp, opening up new application areas for the biopolymer cellulose. The shape, size, network structure and the surface properties of the BC biomaterials are specifically realized directly during biofabrication.

The product profile designates BC as a natural, biocompatible, mechanically stable, and in the body non-degradable bio-and implant material, sterilizable with all usual methods, very good storable and excellent surgically manageable. Regarding its network structure BC is an analogue of collagen, the major extracellular matrix material of the body.

Polymet Jena and Jenpolymers Association Ltd. develop on the basis of the BC innovation supports for cell culturing, scaffolds for tissue engineering, films and shaped bodies for wound care, flat repair materials for the closure of organ defects, inlays for the healing of damaged areas of articular cartilage as well as tubular implants for the replacement of blood vessels.

Our multidisciplinary R & D team cooperates with university hospitals in Cologne, Munich, and Jena: Priv. Doz Dr Wippermann (Heart Center Cologne), Prof. Dr. Kinne (Orthopaedics Jena/ Eisenberg), Priv. Doz. Dr. Heise (Vascular and Visceral surgery Jena), Dr. Lang (Pediatric surgery Munich and Harvard Medical School Boston).